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Censavudine

Cat. No. M30402

All AbMole products are for research use only, cannot be used for human consumption.

Censavudine Structure
Synonym:

OBP-601; BMS-986001; TPN-101

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Quality Control & Documentation
Biological Activity

Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. Censavudine is a potent HIV inhibitor with EC50 ranges from 30 nM to 81 nM and 450 nM to 890 nM for HIV-2 and HIV-1, respectively.

Chemical Information
Molecular Weight 248.23
Formula C12H12N2O4
CAS Number 634907-30-5
Form Solid
Solubility (25°C) DMSO 52 mg/mL (ultrasonic)
Water 10 mg/mL (ultrasonic and warming and heat to 60°C)
Storage 4°C, dry, sealed
References

[1] Richard C Burrell, et al. J Labelled Comp Radiopharm. Synthesis of carbon-14 and stable isotope labeled Censavudine

[2] Junbiao Chang. Acc Chem Res. 4'-Modified Nucleosides for Antiviral Drug Discovery: Achievements and Perspectives

[3] Robert A Smith, et al. Antimicrob Agents Chemother. The Nucleoside Analog BMS-986001 Shows Greater In Vitro Activity against HIV-2 than against HIV-1

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Keywords: Censavudine, OBP-601; BMS-986001; TPN-101 supplier, HIV Protease, inhibitors, activators

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