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Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.
| Molecular Weight | 446.37 |
| Formula | C16H15N4NaO8S |
| CAS Number | 56238-63-2 |
| Form | Solid |
| Solubility (25°C) | 200 mg/ml in Water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] No authors listed. Med Lett Drugs Ther. Cefuroxime sodium (Zinacef)
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