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Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins
| Molecular Weight | 453.45 |
| Formula | C16H15N5O7S2 |
| CAS Number | 79350-37-1 |
| Solubility (25°C) | 55.11 mg/L in Water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Barış Yilmaz, et al. Cefixime-induced hepatotoxicity
[5] K G Naber. Cefixime in urinary tract infections. (Specific studies and literature review)
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