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CCT241161 

Cat. No. M27869

All AbMole products are for research use only, cannot be used for human consumption.

CCT241161  Structure

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Quality Control & Documentation
Biological Activity

CCT241161 is an orally active pan-RAF inhibitor with IC50s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF and BRAF, respectively. CCT241161 shows good activity to in BRAF and NRAS mutant melanomas. CCT241161 also exhibits anticancer cell proliferative activity.

Chemical Information
Molecular Weight 541.62
Formula C28H27N7O3S
CAS Number 1163719-91-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Maria Romina Girotti, et al. Cancer Cell. Paradox-breaking RAF inhibitors that also target SRC are effective in drυg-resistant BRAF mutant melanoma

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  Catalog
Abmole Inhibitor Catalog




Keywords: CCT241161  supplier, Raf, inhibitors, activators

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