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CCI-006 

Cat. No. M29849

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CCI-006  Structure

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Quality Control & Documentation
Biological Activity

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells.

Chemical Information
Molecular Weight 332.33
Formula C15H12N2O5S
CAS Number 292053-42-0
Form Solid
Solubility (25°C) DMSO ≥ 83.33 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Klaartje Somers, et al. Oncogene. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

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  Catalog
Abmole Inhibitor Catalog




Keywords: CCI-006  supplier, Mitochondrial Related, inhibitors, activators

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