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CCG 63802

Cat. No. M6569

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CCG 63802 Structure

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Quality Control & Documentation
Biological Activity

CCG 63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. Selective amongst RGS proteins, with greatest potency at RGS4. Inhibits GTPase accelerating protein activity of RGS4 and blocks its interaction with Gαo. Retains activity under reducing conditions.

Chemical Information
Molecular Weight 450.51
Formula C26H18N4O2S
CAS Number 620112-78-9
Solubility (25°C) DMSO 2.25 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Keegan, et al. Br J Pharmacol. The selective NK receptor agonist senktide excites a subpopulation of dopamine-sensitive neurones in the rat substantia nigra pars compacta in vitro.

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Keywords: CCG 63802 supplier, inhibitors, activators

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