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CBL0137 hydrochloride is an inhibitor of FACT, the histone molecule chaperone. FACT promotes the formation of chromatin transcription complexes. CBL0137 hydrochlorideye also activated p53 and inhibited NF-κB, with EC50 values of 0.37 and 0.47 μM, respectively.
| Molecular Weight | 372.89 |
| Formula | C21H25ClN2O2 |
| CAS Number | 1197397-89-9 |
| Solubility (25°C) | DMSO ≥ 10 mg/mL |
| Storage | 4°C, dry, sealed |
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