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Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM, which has neuroprotective and anti-inflammatory properties in vitro. It has neuroprotective and anti-inflammatory properties in vitro. It can be used in studies related to neurodegenerative diseases.
| Molecular Weight | 336.33 |
| Formula | C16H11F3N2OS |
| CAS Number | 1579991-10-8 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Guanfeng Wang, et al. J Plant Physiol. Casein kinase CK2 structure and activities in plants
[3] Pavlína Janovská, et al. Int J Mol Sci. Targeting Casein Kinase 1 (CK1) in Hematological Cancers
[5] Jit Kong Cheong, et al. Int J Biochem Cell Biol. Casein kinase 1: Complexity in the family
| Related Casein Kinase Products |
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| Silmitasertib (CX-4945)
CX-4945 (Silmitasertib) is a potent small molecule protein kinase inhibitor that selectively binds to and inhibits the enzyme casein kinase II (CK2). |
| PF-4800567
PF-4800567 is a selective, ATP competitive casein kinase 1ε inhibitor with IC50 values of 32 and 711 nM for CK1ε and CK1δ respectively. |
| D4476
D4476 is a selective inhibitor of casein kinase 1 (CK1) and TGF-β type-I receptor (ALK5) with IC50 of 0.3 µM and 0.5 µM, respectively. |
| TTP 22
TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM. |
| TBB
TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively). |
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