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Carotegrast

Cat. No. M30040

All AbMole products are for research use only, cannot be used for human consumption.

Carotegrast Structure
Synonym:

HCA2969

Price and Availability

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Quality Control & Documentation
Biological Activity

Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.

Chemical Information
Molecular Weight 555.41
Formula C27H24Cl2N4O5
CAS Number 401904-75-4
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Taku Kobayashi, et al. Nat Rev Gastroenterol Hepatol. Improving IBD outcomes in the era of many treatment options

[2] Xiaocong Pang, et al. Signal Transduct Target Ther. Targeting integrin pathways: mechanisms and advances in therapy

[3] Sohita Dhillon. Drugs. Carotegrast Methyl: First Approval

[4] Hiroyuki Fukase, et al. Clin Drug Investig. Food Effect on a Single High Dose of Carotegrast Methyl, an Oral Antagonist of α4-Integrin, in Healthy Male Subjects: A Randomised, Placebo-Controlled, Double-Blind Study

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Keywords: Carotegrast, HCA2969 supplier, Integrin, inhibitors, activators

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