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Carotegrast Methyl (AJM300) is an orally effective and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast Methyl, is a specific dual α4β1/α4β7 integrin antagonist. Carotegrast Methyl prevents colitis in mice.
| Molecular Weight | 569.44 |
| Formula | C28H26Cl2N4O5 |
| CAS Number | 401905-67-7 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Sohita Dhillon. Drugs. Carotegrast Methyl: First Approval
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| ATN-161 TFA
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