All AbMole products are for research use only, cannot be used for human consumption.
Carmustine (BiCNU) is a cell-cycle phase nonspecific alkylating antineoplastic agent with ED50 ranging from 5.0 µM to 11.9 µM. It is used in the treatment of several types of brain cancer (including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma and lymphoma (Hodgkin’s and non-Hodgkin). In a study, three lines with O6-AGT activity below 25 fmol/mg protein had carmustine ED50 values ranging from 5.0 µM to 11.9 µM.
| Molecular Weight | 214.05 |
| Formula | C5H9Cl2N3O2 |
| CAS Number | 154-93-8 |
| Solubility (25°C) | DMSO |
| Storage | -20°C, protect from light |
[4] Alison B Fleming, et al. Pharmacokinetics of the carmustine implant
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| Dacarbazine
Dacarbazine (DTIC-Dome; DTIC) is an alkylating agent that acts as a purine nucleotide precursor analog to inhibit purine nucleotide synthesis, thereby inhibiting DNA/RNA Synthesis, and can be used in studies related to melanoma and Hodgkin's lymphoma. |
| Altretamine
Altretamine is an antitumor agent which also acts as a chemosterilant for male houseflies and other insects. |
| Lomustine
Lomustine inhibits cancer cells by damaging the DNA and stops cells from dividing. |
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