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Carbimazole

Cat. No. M2493

All AbMole products are for research use only, cannot be used for human consumption.

Carbimazole Structure
Synonym:

Athyromazole; Neomercazole

Size Price Availability Quantity
100mg USD 30 In stock
500mg USD 40 In stock
1g USD 55 In stock
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Quality Control & Documentation
Biological Activity

Carbimazole is an effective thyroid hormone inhibitor under a class of drugs known as pro-drugs. It is considered a pro-drug because it converts to methimazole after being absorbed by the body, generating an antithyroid action that works against hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (inflammation of the thyroid gland). Carbimazole is an imidazole antithyroid agent.

Chemical Information
Molecular Weight 186.23
Formula C7H10N2O2S
CAS Number 22232-54-8
Solubility (25°C) DMSO 35 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cristina Psomadakis, et al. Carbimazole-induced pancytopaenia

[2] Anam Akmal, et al. Propylthiouracil, and methimazole, and carbimazole-related hepatotoxicity

[3] Ihteshamul Haq, et al. Carbimazole-induced lupus

[4] Nicola Foulds, et al. Carbimazole embryopathy: an emerging phenotype

[5] G Ozenne, et al. Carbimazole-induced acute cholestatic hepatitis

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Keywords: Carbimazole, Athyromazole; Neomercazole supplier, inhibitors, activators

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