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CAM833

Cat. No. M21625

All AbMole products are for research use only, cannot be used for human consumption.

CAM833 Structure
Size Price Availability
5mg USD 400 1-2 Weeks
10mg USD 680 1-2 Weeks
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Biological Activity

CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis.

Chemical Information
Molecular Weight 528.96
Formula C26H26ClFN4O5
CAS Number 2758364-02-0
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Duncan E Scott, et al. Cell Chem Biol. A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

Related RAD51 Products
RI-1

RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.
IBR2

IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair.

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Abmole Inhibitor Catalog




Keywords: CAM833 supplier, RAD51, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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