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BTS 54-505 hydrochloride is a potently active primary amine metabolite of sibutramine, exhibits a similar pharmacological profile to the parent compound. Inhibits serotonin and noradrenalin reuptake more potently than sibutramine in vitro. Reduces food intake in rodents following i.c.v. administration and increases energy expenditure via thermogenesis in vivo.
| Molecular Weight | 288.26 |
| Formula | C15H22NCl.HCl |
| CAS Number | 84484-78-6 |
| Solubility (25°C) | DMSO 28.83 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Bain, et al. Biochem J. The specificities of protein kinase inhibitors: an update.
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