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Bromfenac sodium hydrate

Cat. No. M20792

All AbMole products are for research use only, cannot be used for human consumption.

Bromfenac sodium hydrate Structure
Synonym:

Bromsite, Bromday, Prolensa, Xibrom

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Quality Control & Documentation
Biological Activity

Bromfenac sodium hydrate (Bromsite, Bromday, Prolensa, Xibrom), a brominated nonsteroidal anti-inflammatory drugs (NSAID) with strong in vitro anti-inflammatory potency, is a potent and orally active inhibitor of COX with IC50 of 5.56 nM and 7.45 nM for COX-1 and COX-2, respectively.

Chemical Information
Molecular Weight 766.34
Formula C30H28Br2N2Na2O9
CAS Number 120638-55-3
Solubility (25°C) DMSO 100 mg/mL
Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Antonio Pinna, et al. Eur J Ophthalmol. Bromfenac eyedrops in the treatment of diabetic macular edema: a pilot study

[2] K Kashiwagi, et al. Br J Ophthalmol. Effect of non-steroidal anti-inflammatory ophthalmic solution on intraocular pressure reduction by latanoprost

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Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively).

Nepafenac

Nepafenac is an analgesic selective inhibitor of COX-2.

Ampiroxicam

Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound.

Bromfenac Sodium

Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

  Catalog
Abmole Inhibitor Catalog




Keywords: Bromfenac sodium hydrate, Bromsite, Bromday, Prolensa, Xibrom supplier, COX, inhibitors, activators

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