Free shipping on all orders over $ 500

BRD6688 

Cat. No. M28352

All AbMole products are for research use only, cannot be used for human consumption.

BRD6688  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

BRD6688 is a selective HDAC2 inhibitor. BRD6688 increases H4K12 and H3K9 histone acetylation in primary mouse neuronal cells. BRD6688 crosses the blood brain barrier and rescues the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model.

Chemical Information
Molecular Weight 282.34
Formula C16H18N4O
CAS Number 1404562-17-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Xiao-Min Wang, et al. Mol Cancer Ther. Dysregulation of EAAT2 and VGLUT2 Spinal Glutamate Transports via Histone Deacetylase 2 (HDAC2) Contributes to Paclitaxel-induced Painful Neuropathy

[2] F F Wagner, et al. Chem Sci. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers

Related HDAC Products
Belinostat

Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM.

CUDC-101

CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively.

Givinostat hydrochloride monohydrate

ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively.

Niltubacin

Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.

Tubacin

Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM.

  Catalog
Abmole Inhibitor Catalog




Keywords: BRD6688  supplier, HDAC, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.