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Brazilin

Cat. No. M4489

All AbMole products are for research use only, cannot be used for human consumption.

Brazilin Structure
Size Price Availability Quantity
1mg USD 42 In stock
5mg USD 85 In stock
10mg USD 120 In stock
20mg USD 180 In stock
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Quality Control & Documentation
Biological Activity

Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities.

Chemical Information
Molecular Weight 286.28
Formula C16H14O5
CAS Number 474-07-7
Form Solid
Solubility (25°C) DMSO 30 mg/mL
Ethanol 20 mg/mL
Water ~10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Biji Chatterjee, et al. The phytochemical brazilin suppress DNMT1 expression by recruiting p53 to its promoter resulting in the epigenetic restoration of p21 in MCF7cells

[2] Dania A Nava-Tapia, et al. Brazilin: Biological activities and therapeutic potential in chronic degenerative diseases and cancer

[3] Bin Qi, et al. Brazilin prevents against myocardial ischemia-reperfusion injury through the modulation of Nrf2 via the PKC signaling pathway

[4] George R Nahass, et al. Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium

[5] Xi Wang, et al. Brazilin Treatment Produces Antidepressant- and Anxiolytic-Like Effects in Mice

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Keywords: Brazilin supplier, Apoptosis, inhibitors, activators

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