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BRACO-19 trihydrochloride is a telomerase inhibitor (IC50 = 115 nM). BRACO-19 trihydrochloride inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. BRACO-19 trihydrochloride inhibits growth of uterine tumor xenografts in mice.
| Molecular Weight | 703.14 |
| Formula | C35H43N7O2.3HCl |
| CAS Number | 1177798-88-7 |
| Solubility (25°C) | DMSO 39 mg/mL Water 18 mg/mL |
| Storage | 4°C, dry, sealed |
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