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BQ-788 sodium salt is an effective and selective ETB receptor antagonist with an IC50 of 1.2 nM in human Girrardi heart cells to inhibit ET-1 binding to the ETB receptor. BQ-788 is an enhancer of AQP4(Aquaporin-4).
| Molecular Weight | 663.78 |
| CAS Number | 156161-89-6 |
| Solubility (25°C) | DMSO ≥ 43 mg/mL |
| Storage | -20°C, protect from light, sealed |
| Related Endothelin Receptor Products |
|---|
| Zibotentan
Zibotentan (ZD4054) is a more selective and specific endothelin-A receptor (ETAR) antagonist with an IC50 value of 21 nM. |
| Ambrisentan
Ambrisentan is an orally active, highly selective antagonist of the endothelin-1 type A receptor. |
| Sitaxsentan sodium
Sitaxsentan (TBC-11251) is an orally active, highly selective antagonist of endothelin A receptors. |
| Macitentan
Macitentan is an orally-active, tissue-targeting dual ET receptor antagonist. |
| Bosentan Hydrate
Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. |
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