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BpV (PHEN) Trihydrate, an insulin mimic, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50 of 38 nM, 343 nM, and 920 nM for PTEN, PTP-β, and PTP-1B. BpV (PHEN) TriHydrate inhibits proliferation of protozoan parasites leishmania in vitro.
| Molecular Weight | 404.288 |
| CAS Number | 171202-16-7 |
| Solubility (25°C) | Water ≥ 10 mg/mL |
| Storage | 4°C, dry, sealed |
| Related PTEN Products |
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| SF1670
SF1670 is a pTPN2 and PTEN inhibitor. |
| VO-OHpic trihydrate
VO-OHpic trihydrate is a PTEN (phosphatase and tensin homologue deleted on chromosome 10) inhibitor. |
| bpV(HOpic) potassium salt
BpV(HOpic) is a protein tyrosine phosphatases (PTPs) and a potent PTEN inhibitor with IC50 of 14 nM. |
| Ginkgolic acid 17:1
Ginkgolic acid 17:1, a natural product isolated from Ginkgo biloba, inhibits constitutive and inducible STAT3 activation by inducing PTEN and SHP-1 tyrosine phosphatases. In addition, Ginkgolic acid C17:1 has anticancer activity. |
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