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BPN-15606 besylate is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 besylate lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 besylate has acceptable PK/PD properties, including bioavailability, half-life, and clearance.
| Molecular Weight | 576.64 |
| Formula | C29H29FN6O4S |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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