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BOLD-100 (NKP-1339; IT-139) free base is a ruthenium-based anticancer agent. BOLD-100 free base also is an inhibitor of stress-induced GRP78 upregulation, disrupting endoplasmic reticulum (ER) homeostasis and inducing ER stress and unfolded protein response (UPR). BOLD-100 free base interferes with the complex interplay between ER-stress response, lysosome dynamics, and autophagy execution.
| Molecular Weight | 479.15 |
| Formula | C14H12Cl4N4Ru |
| CAS Number | 783324-98-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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