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BN201 

Cat. No. M28248

All AbMole products are for research use only, cannot be used for human consumption.

BN201  Structure

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Biological Activity

BN201 promotes neuronal differentiation, the differentiation of precursor cells to mature oligodendrocytes (EC50 of 6.3 μM) in vitro, and the myelination of new axons (EC50 of 16.6 μM). BN201 is able to cross the blood-brain barrier by active transport and activate pathways (IGF-1 pathway) associated with the response to stress and neuron survival. BN201 has potently neuroprotective effects.

Chemical Information
Molecular Weight 491.6
Formula C25H38FN5O4
CAS Number 1361200-34-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Pablo Villoslada, et al. Sci Rep. A Phase 1 randomized study on the safety and pharmacokinetics of OCS-05, a neuroprotective disease modifying treatment for Acute Optic Neuritis and Multiple Sclerosis

[2] Pablo Villoslada, et al. Neurotherapeutics. Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation

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Keywords: BN201  supplier, inhibitors, activators

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