Free shipping on all orders over $ 500

BMS-986118 

Cat. No. M28672

All AbMole products are for research use only, cannot be used for human consumption.

BMS-986118  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

BMS-986118 is a potent, orally active, and selective GPR40 agonist with an EC50 of 0.07 µM. BMS-986118 has dual insulinotropic and GLP-1 secretory effects, resulting in robust plasma glucose lowering effects in acute animal models.

Chemical Information
Molecular Weight 540.96
Formula C25H28ClF3N4O4
CAS Number 1610562-74-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jun Shi, et al. J Med Chem. Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists

Related GPR/FFAR Products
GW9508

GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 has anti-inflammatory and anti-atherosclerotic activities. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener.

Fasiglifam (TAK-875) Hemihydrate

Fasiglifam (TAK-875) Hemihydrate is a novel, orally available, selective GPR40 agonist.

OC000459

OC000459 is a potent, selective, and orally active D prostanoid receptor 2 antagonist.

AMG-837

AMG 837 is a potent, orally bioavailable GPR40 agonist with EC50 of 14 nM.

AZD1981

AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1.

  Catalog
Abmole Inhibitor Catalog




Keywords: BMS-986118  supplier, GPR/FFAR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.