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BMS-502

Cat. No. M42321

All AbMole products are for research use only, cannot be used for human consumption.

BMS-502 Structure
Size Price Availability Quantity
5mg USD 370 In stock
10mg USD 590 In stock
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Biological Activity

BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 of 4.6 nM and 2.1 nM.

Chemical Information
Molecular Weight 516.5
Formula C27H22F2N6O3
CAS Number 2407854-18-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Louis Chupak et al. ACS Med Chem Lett. Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization

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BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that enhances T cell initiation of suboptimal tumor antigens by inhibiting DGKζ. In addition, BAY 2965501 induces pERK activation.BAY 2965501 can be used in cancer research.
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Abmole Inhibitor Catalog




Keywords: BMS-502 supplier, DGK, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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