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BMS-1001 hydrochloride is an orally active human PD-L1/PD-1 immune checkpoint inhibitor. BMS-1001 hydrochloride exhibits low-toxicity in cells.
| Molecular Weight | 631.11 |
| Formula | C35H35ClN2O7 |
| CAS Number | 2113650-04-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 12.5 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
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| Panaxadiol
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| BMS202
Bms-202 is an effective non-peptide PD-1/PD-L complex inhibitor with IC50 of 18 nM and KD of 8 μM. Bms-202 directly binds to PD-L1 and blocks the human PD-1/PD-L interaction. Bms-202 has antitumor activity. |
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