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BML-210

Cat. No. M7650

All AbMole products are for research use only, cannot be used for human consumption.

BML-210 Structure
Size Price Availability Quantity
5mg USD 66 In stock
10mg USD 98 In stock
25mg USD 175 In stock
50mg USD 270 In stock
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Quality Control & Documentation
Biological Activity

BML-210 is a histone deacetylase inhibitor. Treatment of A549 cells with BML-210 results in a dose-dependent increase in acetylated histone levels (EC50 = 36 μM). In HeLa extracts, the IC50 for inhibition of HDAC activity is 80 μM.

Chemical Information
Molecular Weight 339.43
Formula C20H25N3O2
CAS Number 537034-17-6
Form Solid
Solubility (25°C) DMSO: >20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Veronika Borutinskaitė, et al. The Histone Deacetylase Inhibitor BML-210 Influences Gene and Protein Expression in Human Promyelocytic Leukemia NB4 Cells via Epigenetic Reprogramming

[2] Veronika V Borutinskaite, et al. Histone deacetylase inhibitor BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells

[3] Veronika V Borutinskaite, et al. Retinoic acid and histone deacetylase inhibitor BML-210 inhibit proliferation of human cervical cancer HeLa cells

[4] Jurate Savickiene, et al. The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines

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Keywords: BML-210 supplier, HDAC, inhibitors, activators

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