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BLT-1

Cat. No. M8217

All AbMole products are for research use only, cannot be used for human consumption.

BLT-1 Structure
Synonym:

Block lipid transport-1

Size Price Availability Quantity
1mg USD 40 In stock
5mg USD 100 In stock
10mg USD 180 In stock
50mg USD 500 In stock
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Quality Control & Documentation
Biological Activity

Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. The compound inhibits both cellular selective lipid uptake of HDL cholesteryl ether and efflux of cellular cholesterol to HDL.

Chemical Information
Molecular Weight 241.4
Formula C12H23N3S
CAS Number 321673-30-7
Solubility (25°C) DMSO 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hirofumi Ohashi, et al. Proc Natl Acad Sci U S A. Reply to Padmanabhan and Dixit: Hepatitis C virus entry inhibitors for optimally boosting direct-acting antiviral-based treatments

[2] Thomas J F Nieland, et al. Biochemistry. Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity

[3] Demetrio Raldua, et al. Toxicol Lett. BLT-1, a specific inhibitor of the HDL receptor SR-BI, induces a copper-dependent phenotype during zebrafish development

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Keywords: BLT-1, Block lipid transport-1 supplier, inhibitors, activators

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