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BL 1249

Cat. No. M6513

All AbMole products are for research use only, cannot be used for human consumption.

BL 1249 Structure

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Quality Control & Documentation
Biological Activity

BL 1249 is a putative potassium channel activator; thought to act as a K2P2.1 (TREK-1) channel opener. Exhibits selectivity for bladder over vascular tissue in vitro and in vivo (EC50 values are 1.26 and 21.0 μM for cultured bladder and aortic tissues respectively).

Chemical Information
Molecular Weight 291.35
Formula C17H17N5
CAS Number 18200-13-0
Solubility (25°C) 1eq. NaOH 29.14 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Elder, et al. Int J Cancer. The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells.

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Keywords: BL 1249 supplier, inhibitors, activators

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