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Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation.
| CAS Number | 1418205-77-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] Egídio Freitas, et al. Drugs. Bimekizumab for the Treatment of Psoriasis
[4] Kristian Reich, et al. N Engl J Med. Bimekizumab versus Secukinumab in Plaque Psoriasis
[5] Richard B Warren, et al. N Engl J Med. Bimekizumab versus Adalimumab in Plaque Psoriasis
| Related IL Receptor/Related Products |
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| Montelukast sodium
Montelukast sodium selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1. |
| VGX-1027
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| Diacerein
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| SC144
SC144 is the first oral active GP130 (IL6-beta) inhibitor. SC144 binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, eliminates Stat3 phosphorylation and nuclear translocation, and further inhibits downstream target gene expression. SC144 inhibited signal transduction induced by GP130 ligand. SC144 induces apoptosis of human ovarian cancer cells. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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