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Bilobetin is a biflavonoid extracted from Ginkgo biloba with a variety of biological functions. Bilobetin has significant antioxidant activity, scavenging free radicals and reducing cellular damage from oxidative stress. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity.
| Molecular Weight | 552.48 |
| Formula | C31H20O10 |
| CAS Number | 521-32-4 |
| Solubility (25°C) | DMSO 110 mg/mL |
| Storage | 4°C, protect from light |
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