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Bifemelane hydrochloride

Cat. No. M30381

All AbMole products are for research use only, cannot be used for human consumption.

Bifemelane hydrochloride Structure
Synonym:

MCI-2016

Size Price Availability Quantity
5mg USD 75 In stock
10mg USD 130 In stock
25mg USD 250 In stock
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Quality Control & Documentation
Biological Activity

Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A), with a Ki of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a Ki of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease.

Chemical Information
Molecular Weight 305.84
Formula C18H24ClNO
CAS Number 62232-46-6
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage 4°C, protect from light, dry, sealed
References

[1] I Miyazaki, et al. Neurochem Res. Bifemelane hydrochloride protects against cytotoxicity of hydrogen peroxide on cultured rat neuroblastoma cell line

[2] N Ogawa, et al. Clin Ther. Comparison of the effects of bifemelane hydrochloride and indeloxazine hydrochloride on scopolamine hydrobromide-induced impairment in radial maze performance

[3] M Egawa, et al. Neuropharmacology. Effects of bifemelane hydrochloride on cortical neuronal activity in cats

[4] T Mitsuma, et al. Exp Clin Endocrinol. Bifemelane hydrochloride reduces plasma beta-endorphin-like immunoreactivity levels in rats

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Keywords: Bifemelane hydrochloride, MCI-2016 supplier, Monoamine Oxidase, inhibitors, activators

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