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BI 99179

Cat. No. M14430

All AbMole products are for research use only, cannot be used for human consumption.

BI 99179 Structure
Size Price Availability Quantity
5mg USD 105 In stock
10mg USD 165 In stock
25mg USD 330 In stock
50mg USD 520 In stock
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Quality Control & Documentation
Biological Activity

BI 99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats.

Chemical Information
Molecular Weight 391.46
CAS Number 1291779-76-4
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Prosanta K Singha, et al. Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human cancer cells

[2] Jrg T Kley, et al. Discovery of BI 99179, a potent and selective inhibitor of type I fatty acid synthase with central exposure

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Keywords: BI 99179 supplier, FAS, inhibitors, activators

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