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BI-9321

Cat. No. M10796

All AbMole products are for research use only, cannot be used for human consumption.

BI-9321 Structure

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Quality Control & Documentation
Biological Activity

BI-9321 is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM.

Chemical Information
Molecular Weight 360.43
Formula C22H21FN4
CAS Number 2387510-86-1
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jark Bttcher, et al. Nat Chem Biol. Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

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  Catalog
Abmole Inhibitor Catalog




Keywords: BI-9321 supplier, Histone Methyltransferase, inhibitors, activators

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