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BI-2545 

Cat. No. M29313

All AbMole products are for research use only, cannot be used for human consumption.

BI-2545  Structure

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Quality Control & Documentation
Biological Activity

BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC50s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively.

Chemical Information
Molecular Weight 527.42
Formula C23H19F6N5O3
CAS Number 2162961-71-7
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Christian A Kuttruff, et al. ACS Med Chem Lett. Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo

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  Catalog
Abmole Inhibitor Catalog




Keywords: BI-2545  supplier, PDE, inhibitors, activators

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