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BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.
| Molecular Weight | 566.45 |
| Formula | C30H26Cl2FN3O3 |
| CAS Number | 1818291-27-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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