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Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.
| Molecular Weight | 547.06 |
| Formula | C21H25ClN2O3.C6H6O3S |
| CAS Number | 190786-44-8 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Leonard Bielory, et al. Bepotastine besilate for the treatment of pruritus
| Related Histamine Receptor Products |
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Ciproxifan is an orally bioavailable, extremely potent histamine H3 inverse agonist/antagonist. |
| Antazoline hydrochloride
Antazoline hydrochloride is a first generation antihistamine, binding to the histamine H1 receptor and blocking the action of endogenous histamine. |
| Azacyclonol
Azacyclonol, also known as γ-pipradol, which diminishes hallucinations in psychotic individuals. |
| Azatadine dimaleate
Azatadine dimaleate is an antihistamine and anticholinergic compound with IC50 of 6.5nM and 10nM, respectively. |
| Buclizine hydrochloride
Buclizine hydrochloride is an antihistamine and anticholinergic of the piperazine derivative family. |
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