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Benztropine

Cat. No. M30719

All AbMole products are for research use only, cannot be used for human consumption.

Benztropine Structure
Synonym:

Benzatropine; Benzotropine

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Quality Control & Documentation
Biological Activity

Benztropine (Benzatropine; Benzotropine) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects.

Chemical Information
Molecular Weight 307.43
Formula C21H25NO
CAS Number 86-13-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Robert D Gibbons, et al. Psychiatry Res. Benztropine and suicide attempts and intentional self-harm

[2] Richard B Rothman, et al. Biochem Pharmacol. Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction

[3] M J Lynch, et al. Med Sci Law. Fatal benztropine toxicity

[4] R F Grace. Adverse Drug React Toxicol Rev. Benztropine abuse and overdose--case report and review

[5] J V Ananth, et al. Can Psychiatr Assoc J. Benztropine psychosis

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Benztropine mesylate

Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Benztropine mesylate is a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects. Benztropine mesylate is also an anti-histamine agent and a dopamine re-uptake inhibitor.

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Keywords: Benztropine, Benzatropine; Benzotropine supplier, Dopamine Receptor, inhibitors, activators

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