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Benzbromarone is a URAT1 inhibitor that inhibits MDCKII cells over-expressing URAT1 with an IC50 of 0.190 μM. Benzbromarone is also a CYP2C9 inhibitor, it binds to CYP2C9 with Ki value of 19.3 nM.
| Molecular Weight | 424.08 |
| Formula | C17H12Br2O3 |
| CAS Number | 3562-84-3 |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] No authors listed. Benzbromarone
[3] Valderilio Feij Azevedo, et al. Benzbromarone in the treatment of gout
[4] Peng Sun, et al. Benzbromarone aggravates hepatic steatosis in obese individuals
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