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Bempegaldesleukin

Cat. No. M24858

All AbMole products are for research use only, cannot be used for human consumption.

Bempegaldesleukin Structure
Synonym:

NKTR-214 BEMPEG

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Quality Control & Documentation
Biological Activity

Bempegaldesleukin (NKTR-214), a PEGylated interleukin-2 (IL-2), is an immunostimulatory IL-2 prodrug acting as a CD122-preferential IL-2 pathway agonist. Bempegaldesleukin can stimulate an antitumor immune response.

Chemical Information
CAS Number 1939126-74-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Arlene O Siefker-Radtke, et al. Eur Urol. Bempegaldesleukin plus Nivolumab in First-line Metastatic Urothelial Carcinoma: Results from PIVOT-02

[2] Adi Diab, et al. J Clin Oncol. Bempegaldesleukin Plus Nivolumab in First-Line Metastatic Melanoma

[3] Meenu Sharma, et al. Nat Commun. Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy

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Keywords: Bempegaldesleukin, NKTR-214 BEMPEG supplier, IL Receptor/Related, inhibitors, activators

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