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Befotertinib

Cat. No. M28940

All AbMole products are for research use only, cannot be used for human consumption.

Befotertinib Structure
Synonym:

D-0316

Price and Availability

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Quality Control & Documentation
Biological Activity

Befotertinib (D-0316) is the third-generation EGFR tyrosine kinase inhibitor. Befotertinib can be used for the research of EGFR T790M-positive non-small cell lung cancer (NSCLC).

Chemical Information
Molecular Weight 567.61
Formula C29H32F3N7O2
CAS Number 1835667-63-4
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C)
Storage Powder -20°C
References

[1] Jessica Menis, et al. Lancet Respir Med. Befotertinib-a viable alternative in EGFR-mutant advanced NSCLC?

[2] Hua Li, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Simultaneous quantitation of befotertinib (D-0316) and its metabolite D-0865 in human plasma by LC-MS/MS method

[3] Sally C M Lau, et al. J Thorac Oncol. And Still They Come Over Troubled Waters: Can Asia's Third-Generation EGFR Tyrosine Kinase Inhibitors (Furmonertinib, Aumolertinib, Rezivertinib, Limertinib, Befotertinib, SH-1028, and Lazertinib) Affect Global Treatment of EGFR+ NSCLC

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Keywords: Befotertinib, D-0316 supplier, EGFR/HER2, inhibitors, activators

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