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Bectumomab

Cat. No. M24722

All AbMole products are for research use only, cannot be used for human consumption.

Bectumomab Structure
Synonym:

IMMU-LL 2

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Quality Control & Documentation
Biological Activity

Bectumomab (IMMU-LL 2) is an humanized IgG2a mAb against human CD22 (antigen). Bectumomab is also an anti-lymphoma antibody fragment. Bectumomab can be used for imaging in combination with technetium 99 (Tc99m LL2 Fab). Moreover, Bectumomab examines in the staging of recurrent or newly diagnosed non-Hodgkin's lymphoma (NHL) and to assess targeting before radioimmunotherapy (RIT).

Chemical Information
CAS Number 158318-63-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] D Lamonica, et al. Cancer Biother Radiopharm. Radioimmunoscintigraphy (RIS) with bectumomab (Tc99m labeled IMMU-LL2, Lymphoscan) in the assessment of recurrent non-Hodgkin's lymphoma (NHL)

[2] D L Newton, et al. Blood. Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma

[3] L B Shih, et al. Int J Cancer. Internalization and intracellular processing of an anti-B-cell lymphoma monoclonal antibody, LL2

[4] S Murthy, et al. Eur J Nucl Med. Lymphoma imaging with a new technetium-99m labelled antibody, LL2

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Keywords: Bectumomab, IMMU-LL 2 supplier, inhibitors, activators

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