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BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI does not inhibit DUSP5.
| Molecular Weight | 317.42 |
| CAS Number | 1245792-51-1 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Ravikiran Mane, et al. BCI for stroke rehabilitation: motor and beyond
[3] Madiha Tariq, et al. EEG-Based BCI Control Schemes for Lower-Limb Assistive-Robots
[4] Kaitlyn Casimo, et al. BCI Use and Its Relation to Adaptation in Cortical Networks
[5] Gerwin Schalk, et al. BCI2000: a general-purpose brain-computer interface (BCI) system
| Related Phosphatase Products |
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| CCT007093
CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
| Microcystin-LR
Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| Sal003
Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor. |
| Razuprotafib
Razuprotafib (AKB-9778) is an effective selective inhibitor of VE-PTP (HPTPß) catalytic activity (IC50=17 pM). |
| β-Glycerophosphate disodium salt hydrate
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. |
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