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Bay K 8644

Cat. No. M14190

All AbMole products are for research use only, cannot be used for human consumption.

Bay K 8644 Structure
Synonym:

(±)-Bay K 8644

Size Price Availability Quantity
5mg USD 95 In stock
10mg USD 150 In stock
25mg USD 300 In stock
50mg USD 465 In stock
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Quality Control & Documentation
Biological Activity

Bay K 8644, a dihydropyridine compound, is a specific L-type Ca2+ channel agonist. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel.

Chemical Information
Molecular Weight 356.3
CAS Number 71145-03-4
Solubility (25°C) DMSO 83.33 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] H Satoh, et al. Bay K 8644 increases resting Ca2+ spark frequency in ferret ventricular myocytes independent of Ca influx: contrast with caffeine and ryanodine effects

[2] S Heisler, et al. BAY-K-8644-stimulated amylase secretion from pancreatic acinar cells

[3] N Ives, et al. BAY k 8644, a calcium channel agonist, reverses hypotension in endotoxin-shocked rats

[4] N Tohse, et al. Bay K 8644 enhances Ca2+ channel activities in embryonic chick heart cells without prolongation of open times

[5] L Wu, et al. Bay K-8644 in different solvents acts as a transient calcium channel antagonist and a long-lasting calcium channel agonist

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Keywords: Bay K 8644, (±)-Bay K 8644 supplier, Calcium Channel, inhibitors, activators

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