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BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy.
| Molecular Weight | 288.34 |
| Formula | C15H20N4O2 |
| CAS Number | 2109805-96-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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