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Bakuchiol is a phytoestrogens from psoralea seeds that have anti-tumor and other effects. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2), with IC50 values values of 40.9 μM and 7.28 μM, respectively.
| Molecular Weight | 256.38 |
| Formula | C18H24O |
| CAS Number | 10309-37-2 |
| Form | Liquid (density 0.963 g/mL) |
| Solubility (25°C) | DMSO 45 mg/mL |
| Storage | -20°C, protect from light |
[2] Natalia M K Spierings. Cosmetic commentary: Is bakuchiol the new "skincare hero"?
[3] Jordan V Wang, et al. Bakuchiol as a Trendy Ingredient in Skincare: Recent Evidence
| Related Carboxylesterase Products |
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| Nevadensin
Nevadensin (Lysionotin) is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. |
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