Free shipping on all orders over $ 500

Baccatin III

Cat. No. M16492

All AbMole products are for research use only, cannot be used for human consumption.

Baccatin III Structure
Size Price Availability Quantity
5mg USD 50 In stock
10mg USD 90 In stock
20mg USD 150 In stock
50mg USD 250 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?
Quality Control & Documentation
Biological Activity

Baccatin III is an orally available, selective inhibitor of the TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation. Baccatin III targets the AKT/STAT6 and Smad2/3 pathways, blocking TGF-β1-induced fibroblast differentiation and MDSC-mediated immunosuppression. Baccatin III exerts anti-inflammatory and anti-fibrotic effects by inhibiting macrophage activation and extracellular matrix deposition.

Chemical Information
Molecular Weight 586.63
Formula C31H38O11
CAS Number 27548-93-2
Solubility (25°C) DMSO 29 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hao Wang, et al. Acta Pharm Sin B. Construction of acetyl-CoA and DBAT hybrid metabolic pathway for acetylation of 10-deacetylbaccatin III to baccatin III

[2] Balendra Sah, et al. 3 Biotech. Evaluation of the anticancer activity of enzymatically synthesized Baccatin III: an intermediate precursor of Taxol®

[3] Yunjuan Nie, et al. Int Immunopharmacol. Baccatin III ameliorates bleomycin-induced pulmonary fibrosis via suppression of TGF-β1 production and TGF-β1-induced fibroblast differentiation

[4] Lin-Feng You, et al. Mol Biotechnol. Optimization of Baccatin III Production by Cross-Linked Enzyme Aggregate of Taxoid 10β-O-Acetyltransferase

[5] Young-Hee Lee, et al. Int Immunopharmacol. Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells

Related Diterpenoids Products
ent-13,16β,17-Trihydroxykauran-19-oic acid

ent-13,16β,17-Trihydroxykauran-19-oic acid is a natural product for research related to life sciences.
ent-16β,17-Dihydroxykauran-19-oic acid

ent-16β,17-Dihydroxykauran-19-oic acid
Deacetylpseudolaric acid C2

Deacetylpseudolaric acid C2
7-Oxodehydroabietic acid

7-Oxodehydroabietic acid
Siegeskaurolic acid

Siegeskaurolic acid
  Catalog
Abmole Inhibitor Catalog




Keywords: Baccatin III supplier, Diterpenoids, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.