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Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains.
| Molecular Weight | 322.68 |
| Formula | C9H12ClFN6O4 |
| CAS Number | 1333126-31-0 |
| Form | Solid |
| Solubility (25°C) | Water 125 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
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