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AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma.
| Molecular Weight | 457.83 |
| Formula | C20H19ClF3N3O4 |
| CAS Number | 2042347-69-1 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 250 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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