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AZD8309 

Cat. No. M29931

All AbMole products are for research use only, cannot be used for human consumption.

AZD8309  Structure

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Quality Control & Documentation
Biological Activity

AZD8309 is an orally active antagonist of CXCR2. AZD8309 has the ability to regulate the transmigration of neutrophils. AZD8309 can be used in the study of inflammatory diseases.

Chemical Information
Molecular Weight 384.42
Formula C15H14F2N4O2S2
CAS Number 333742-48-6
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage 4°C, protect from light, dry, sealed
References

[1] Sudarshan R Malla, et al. Pancreatology. Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis

[2] Brian R Leaker, et al. Respir Res. Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist

[3] R Virtala, et al. Clin Exp Allergy. Airway inflammation evaluated in a human nasal lipopolysaccharide challenge model by investigating the effect of a CXCR2 inhibitor

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Keywords: AZD8309  supplier, CXCR, inhibitors, activators

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